Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice from Salmonella Infection

BACKGROUND & AIMS: Intestinal epithelial cells aid in mucosal defense by providing a physical barrier against entry of pathogenic bacteria and secreting anti-microbial peptides (AMPs). Autophagy is an important component of immune homeostasis. However, little is known about its role in specific...

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Main Authors: Conway, Kara L., Kuballa, Petric, Song, Joo-Hye, Patel, Khushbu K., Castoreno, Adam B., Yilmaz, Omer H., Jijon, Humberto B., Zhang, Mei, Aldrich, Leslie N., Villablanca, Eduardo J., Peloquin, Joanna M., Goel, Gautam, Lee, In-Ah, Mizoguchi, Emiko, Shi, Hai Ning, Bhan, Atul K., Shaw, Stanley Y., Schreiber, Stuart L., Virgin, Herbert W., Shamji, Alykhan F., Stappenbeck, Thaddeus S., Reinecker, Hans C., Xavier, Ramnik J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840157/
https://ncbi.nlm.nih.gov/pubmed/23973919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.08.035
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