Artificial domain duplication replicates evolutionary history of ketol‐acid reductoisomerases

Por Cahn, Jackson K.B., Brinkmann‐Chen, Sabine, Buller, Andrew R., Arnold, Frances H.
Publicado no Protein Sci (2015)

A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation

Por Murciano-Calles, Javier, Romney, David K., Brinkmann-Chen, Sabine, Buller, Andrew R., Arnold, Frances H.
Publicado no Angew Chem Int Ed Engl (2016)

Enantioselective, Intermolecular Benzylic C–H Amination Catalyzed by an Engineered Iron-Heme Enzyme

Por Prier, Christopher K., Zhang, Ruijie K., Buller, Andrew R., Brinkmann-Chen, Sabine, Arnold, Frances H.
Publicado no Nat Chem (2017)

Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation

Por Buller, Andrew R., Brinkmann-Chen, Sabine, Romney, David K., Herger, Michael, Murciano-Calles, Javier, Arnold, Frances H.
Publicado no Proc Natl Acad Sci U S A (2015)

Synthesis of β-branched tryptophan analogs using an engineered subunit of tryptophan synthase

Por Herger, Michael, van Roye, Paul, Romney, David K., Brinkmann-Chen, Sabine, Buller, Andrew R., Arnold, Frances H.
Publicado no J Am Chem Soc (2016)

Structural, Functional, and Spectroscopic Characterization of the Substrate Scope of the Novel Nitrating Cytochrome P450 TxtE

Por Dodani, Sheel C., Cahn, Jackson K. B., Heinisch, Tillmann, Brinkmann-Chen, Sabine, McIntosh, John A., Arnold, Frances H.
Publicado no Chembiochem (2014)

Cofactor specificity motifs and the induced fit mechanism in Class I ketol-acid reductoisomerases

Por Cahn, Jackson K.B., Brinkmann-Chen, Sabine, Spatzal, Thomas, Wiig, Jared A., Buller, Andrew R., Einsle, Oliver, Hu, Yilin, Ribbe, Markus W., Arnold, Frances H.
Publicado no Biochem J (2015)

General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH

Por Brinkmann-Chen, Sabine, Flock, Tilman, Cahn, Jackson K. B., Snow, Christopher D., Brustad, Eric M., McIntosh, John A., Meinhold, Peter, Zhang, Liang, Arnold, Frances H.
Publicado em 2013