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Enantioselective, Intermolecular Benzylic C–H Amination Catalyzed by an Engineered Iron-Heme Enzyme

C–H bonds are ubiquitous structural units of organic molecules; while these bonds are generally considered to be chemically inert, the recent emergence of methods for C–H functionalization promises to transform the way synthetic chemistry is performed. The intermolecular amination of C–H bonds repre...

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Detalhes bibliográficos
Publicado no:Nat Chem
Main Authors: Prier, Christopher K., Zhang, Ruijie K., Buller, Andrew R., Brinkmann-Chen, Sabine, Arnold, Frances H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555633/
https://ncbi.nlm.nih.gov/pubmed/28644476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2783
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