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Structural, Functional, and Spectroscopic Characterization of the Substrate Scope of the Novel Nitrating Cytochrome P450 TxtE
A novel cytochrome P450 enzyme TxtE was recently shown to catalyze the direct aromatic nitration of L-tryptophan. This unique chemistry induced us to ask whether TxtE could serve as a platform for engineering new nitration biocatalysts, as a replacement for current harsh synthetic methods. As a firs...
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| Publicado no: | Chembiochem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4260628/ https://ncbi.nlm.nih.gov/pubmed/25182183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402241 |
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