Deciphering membrane protein structures from protein sequences

Por Flock, Tilman, Venkatakrishnan, AJ, Vinothkumar, KR, Babu, M Madan
Publicado em 2012

How do disordered regions achieve comparable functions to structured domains?

Por Latysheva, Natasha S, Flock, Tilman, Weatheritt, Robert J, Chavali, Sreenivas, Babu, M Madan
Publicado no Protein Sci (2015)

Molecular Principles of Gene Fusion Mediated Rewiring of Protein Interaction Networks in Cancer

Por Latysheva, Natasha S., Oates, Matt E., Maddox, Louis, Flock, Tilman, Gough, Julian, Buljan, Marija, Weatheritt, Robert J., Babu, M. Madan
Publicado no Mol Cell (2016)

Exploiting sequence and stability information for directing nanobody stability engineering

Por Kunz, Patrick, Flock, Tilman, Soler, Nicolas, Zaiss, Moritz, Vincke, Cécile, Sterckx, Yann, Kastelic, Damjana, Muyldermans, Serge, Hoheisel, Jörg D.
Publicado no Biochim Biophys Acta (2017)

Universal allosteric mechanism for Gα activation by GPCRs

Por Flock, Tilman, Ravarani, Charles N. J., Sun, Dawei, Venkatakrishnan, A. J., Kayikci, Melis, Tate, Christopher G., Veprintsev, Dmitry B., Babu, M. Madan
Publicado no Nature (2015)

General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH

Por Brinkmann-Chen, Sabine, Flock, Tilman, Cahn, Jackson K. B., Snow, Christopher D., Brustad, Eric M., McIntosh, John A., Meinhold, Peter, Zhang, Liang, Arnold, Frances H.
Publicado em 2013

Probing Gα(i1) Protein Activation at Single Amino Acid Resolution

Por Sun, Dawei, Flock, Tilman, Deupi, Xavier, Maeda, Shoji, Matkovic, Milos, Mendieta, Sandro, Mayer, Daniel, Dawson, Roger, Schertler, Gebhard F.X., Madan Babu, M., Veprintsev, Dmitry B.
Publicado no Nat Struct Mol Biol (2015)

Diverse activation pathways in class A GPCRs converge near the G protein-coupling region

Por Venkatakrishnan, A. J., Deupi, Xavier, Lebon, Guillaume, Heydenreich, Franziska M., Flock, Tilman, Miljus, Tamara, Balaji, Santhanam, Bouvier, Michel, Veprintsev, Dmitry B., Tate, Christopher G., Schertler, Gebhard F. X., Babu, M. Madan
Publicado no Nature (2016)