Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas

Por Squatrito, Massimo, Brennan, Cameron W., Helmy, Karim, Huse, Jason T., Petrini, John H., Holland, Eric C.
Publicado em 2010

Perivascular Nitric Oxide Activates Notch Signaling and Promotes Stem-like Character in PDGF-induced Glioma Cells

Por Charles, Nikki, Ozawa, Tatsuya, Squatrito, Massimo, Bleau, Anne-Marie, Brennan, Cameron W., Hambardzumyan, Dolores, Holland, Eric C.
Publicado em 2010

PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells

Por Bleau, Anne-Marie, Hambardzumyan, Dolores, Ozawa, Tatsuya, Fomchenko, Elena I., Huse, Jason T., Brennan, Cameron W., Holland, Eric C.
Publicado em 2009

Loss of imprinting and marked gene elevation are two forms of aberrant IGF2 expression in colorectal cancer

Por Cheng, Yu-Wei, Idrees, Kamran, Shattock, Richard, Khan, Sajid A., Zeng, Zhaoshi, Brennan, Cameron W., Paty, Philip, Barany, Francis
Publicado em 2010

Double minute chromosomes in glioblastoma multiforme are revealed by precise reconstruction of oncogenic amplicons

Por Sanborn, J. Zachary, Salama, Sofie R., Grifford, Mia, Brennan, Cameron W., Mikkelsen, Tom, Jhanwar, Suresh, Katzman, Sol, Chin, Lynda, Haussler, David
Publicado em 2013

Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

Por LeFave, Clare V, Squatrito, Massimo, Vorlova, Sandra, Rocco, Gina L, Brennan, Cameron W, Holland, Eric C, Pan, Ying-Xian, Cartegni, Luca
Publicado em 2011

Candidate pathways for promoting differentiation or quiescence of oligodendrocyte progenitor-like cells in glioma

Por Dougherty, Joseph D., Fomchenko, Elena I., Akuffo, Afua A., Schmidt, Eric, Helmy, Karim Y., Bazzoli, Elena, Brennan, Cameron W., Holland, Eric C., Milosevic, Ana
Publicado em 2012

Suppression of MicroRNA-9 by Mutant EGFR Signaling Upregulates FOXP1 to Enhance Glioblastoma Tumorigenicity

Por Gomez, German G., Volinia, Stefano, Croce, Carlo M., Zanca, Ciro, Li, Ming, Emnett, Ryan, Gutmann, David H., Brennan, Cameron W., Furnari, Frank B., Cavenee, Webster K
Publicado em 2014

Quantitative assessment of intragenic receptor tyrosine kinase deletions in primary glioblastomas: their prevalence and molecular correlates

Por Kastenhuber, Edward R., Huse, Jason T., Berman, Samuel H., Pedraza, Alicia, Zhang, Jianan, Suehara, Yoshiyuki, Viale, Agnes, Cavatore, Magali, Heguy, Adriana, Szerlip, Nicholas, Ladanyi, Marc, Brennan, Cameron W.
Publicado em 2013

Transcriptional diversity of long-term glioblastoma survivors

Por Gerber, Naamit K., Goenka, Anuj, Turcan, Sevin, Reyngold, Marsha, Makarov, Vladimir, Kannan, Kasthuri, Beal, Kathryn, Omuro, Antonio, Yamada, Yoshiya, Gutin, Phillip, Brennan, Cameron W., Huse, Jason T., Chan, Timothy A.
Publicado em 2014

Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis

Por Ortiz, Berenice, Fabius, Armida W. M., Wu, Wei H., Pedraza, Alicia, Brennan, Cameron W., Schultz, Nikolaus, Pitter, Kenneth L., Bromberg, Jacqueline F., Huse, Jason T., Holland, Eric C., Chan, Timothy A.
Publicado em 2014

Long-term risk of radionecrosis and imaging changes after stereotactic radiosurgery for brain metastases

Por Kohutek, Zachary A., Yamada, Yoshiya, Chan, Timothy A., Brennan, Cameron W., Tabar, Viviane, Gutin, Philip H., Yang, T. Jonathan, Rosenblum, Marc K., Ballangrud, Åse, Young, Robert J., Zhang, Zhigang, Beal, Kathryn
Publicado no J Neurooncol (2015)

Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response

Por Szerlip, Nicholas J., Pedraza, Alicia, Chakravarty, Debyani, Azim, Mohammad, McGuire, Jeremy, Fang, Yuqiang, Ozawa, Tatsuya, Holland, Eric C., Huse, Jason T., Jhanwar, Suresh, Leversha, Margaret A., Mikkelsen, Tom, Brennan, Cameron W.
Publicado em 2012

Sleeping Beauty Mouse Models Identify Candidate Genes Involved in Gliomagenesis

Por Vyazunova, Irina, Maklakova, Vilena I., Berman, Samuel, De, Ishani, Steffen, Megan D., Hong, Won, Lincoln, Hayley, Morrissy, A. Sorana, Taylor, Michael D., Akagi, Keiko, Brennan, Cameron W., Rodriguez, Fausto J., Collier, Lara S.
Publicado no PLoS One (2014)

Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge

Por Sturm, Dominik, Bender, Sebastian, Jones, David T.W., Lichter, Peter, Grill, Jacques, Becher, Oren, Hawkins, Cynthia, Majewski, Jacek, Jones, Chris, Costello, Joseph F., Iavarone, Antonio, Aldape, Kenneth, Brennan, Cameron W., Jabado, Nada, Pfister, Stefan M.
Publicado em 2014

MEF promotes stemness in the pathogenesis of gliomas

Por Bazzoli, Elena, Pulvirenti, Teodoro, Oberstadt, Moritz C., Perna, Fabiana, Wee, Boyoung, Schultz, Nikolaus, Huse, Jason T., Fomchenko, Elena I., Voza, Francesca, Tabar, Viviane, Brennan, Cameron W., DeAngelis, Lisa M., Nimer, Stephen D., Holland, Eric C., Squatrito, Massimo
Publicado em 2012

PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

Por Ozawa, Tatsuya, Brennan, Cameron W., Wang, Lu, Squatrito, Massimo, Sasayama, Takashi, Nakada, Mitsutoshi, Huse, Jason T., Pedraza, Alicia, Utsuki, Satoshi, Yasui, Yoshie, Tandon, Adesh, Fomchenko, Elena I., Oka, Hidehiro, Levine, Ross L., Fujii, Kiyotaka, Ladanyi, Marc, Holland, Eric C.
Publicado em 2010

Genomic dissection of the epidermal growth factor receptor (EGFR)/PI3K pathway reveals frequent deletion of the EGFR phosphatase PTPRS in head and neck cancers

Por Morris, Luc G. T., Taylor, Barry S., Bivona, Trever G., Gong, Yongxing, Eng, Stephanie, Brennan, Cameron W., Kaufman, Andrew, Kastenhuber, Edward R., Banuchi, Victoria E., Singh, Bhuvanesh, Heguy, Adriana, Viale, Agnes, Mellinghoff, Ingo K., Huse, Jason, Ganly, Ian, Chan, Timothy A.
Publicado em 2011

A Brain Tumor Molecular Imaging Strategy Using A New Triple-Modality MRI-Photoacoustic-Raman Nanoparticle

Por Kircher, Moritz F, de la Zerda, Adam, Jokerst, Jesse V, Zavaleta, Cristina L, Kempen, Paul J, Mittra, Erik, Pitter, Ken, Huang, Ruimin, Campos, Carl, Habte, Frezghi, Sinclair, Robert, Brennan, Cameron W., Mellinghoff, Ingo K, Holland, Eric C, Gambhir, Sanjiv S
Publicado em 2012

A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival

Por Zheng, Siyuan, Fu, Jun, Vegesna, Rahulsimham, Mao, Yong, Heathcock, Lindsey E., Torres-Garcia, Wandaliz, Ezhilarasan, Ravesanker, Wang, Shuzhen, McKenna, Aaron, Chin, Lynda, Brennan, Cameron W., Yung, W.K. Alfred, Weinstein, John N., Aldape, Kenneth D., Sulman, Erik P., Chen, Ken, Koul, Dimpy, Verhaak, Roel G.W.
Publicado em 2013