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Loss of imprinting and marked gene elevation are two forms of aberrant IGF2 expression in colorectal cancer
Loss of imprinting (LOI) of IGF2 is a common event in many cancers and typically activates the maternally silenced allele. The resulting biallelic IGF2 expression correlates strongly with the hypomethylation of a differentially methylated region (DMR) near its promoter. It has also been shown that I...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , |
|---|---|
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
2010
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3270092/ https://ncbi.nlm.nih.gov/pubmed/19957330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25086 |
| ট্যাগগুলো: |
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