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High incidence of LRAT promoter hypermethylation in colorectal cancer correlates with tumor stage

Lecithin:retinol acyltransferase (LRAT) is a major enzyme involved in vitamin A/retinol metabolism, which regulates various physiological processes like cell proliferation and differentiation. LRAT expression is reduced in numerous cancers, yet the underlying mechanisms have remained undefined. We h...

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Detalhes bibliográficos
Publicado no:Med Oncol
Main Authors: Cheng, Yu-Wei, Pincas, Hanna, Huang, Jianmin, Zachariah, Emmanuel, Zeng, Zhaoshi, Notterman, Daniel A., Paty, Philip, Barany, Francis
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386722/
https://ncbi.nlm.nih.gov/pubmed/25260806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12032-014-0254-7
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