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High sensitivity EndoV mutation scanning through real-time ligase proofreading

The ability to associate mutations in cancer genes with the disease and its subtypes is critical for understanding oncogenesis and identifying biomarkers for clinical diagnosis. A two-step mutation scanning method that sequentially used endonuclease V (EndoV) to nick at mismatches and DNA ligase to...

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Détails bibliographiques
Auteurs principaux: Pincas, Hanna, Pingle, Maneesh R., Huang, Jianmin, Lao, Kaiqin, Paty, Philip B., Friedman, Alan M., Barany, Francis
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC528826/
https://ncbi.nlm.nih.gov/pubmed/15514109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh150
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