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Genetic Variants in Germline TP53 and MDM2 SNP309 Are Not Associated With Early Onset Colorectal Cancer

BACKGROUND AND OBJECTIVES: Colorectal cancer (CRC) arising in patients under age 30 is a rare disease, and few cases have been reported within Li-Fraumeni kindreds. To determine how often alterations in the p53 pathway genes contribute to disease susceptibility, we have evaluated patients with early...

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Detalhes bibliográficos
Publicado no:J Surg Oncol
Main Authors: KHAN, SAJID A., IDREES, KAMRAN, FORSLUND, ANN, ZENG, ZHAOSHI, ROSENBERG, SHOSHANA, PINCAS, HANNA, BARANY, FRANCIS, OFFIT, KENNETH, LAQUAGLIA, MICHAEL P., PATY, PHILIP B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381874/
https://ncbi.nlm.nih.gov/pubmed/18381604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jso.20996
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