Impact of TP53 Codon 72 and MDM2 SNP 309 Polymorphisms in Pancreatic Ductal Adenocarcinoma

Single-nucleotide polymorphisms (SNPs) of TP53 (codon 72, rs1042522) and MDM2 promoter (SNP 309, rs2279744) have been associated with risk for various human cancers. However, studies analyzing these polymorphisms in pancreatic ductal adenocarcinoma (PDAC) are lacking. We investigated TP53 codon 72 a...

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Vydáno v:PLoS One
Hlavní autoři: Hori, Yasuki, Miyabe, Katsuyuki, Yoshida, Michihiro, Nakazawa, Takahiro, Hayashi, Kazuki, Naitoh, Itaru, Shimizu, Shuya, Kondo, Hiromu, Nishi, Yuji, Umemura, Shuichiro, Kato, Akihisa, Ohara, Hirotaka, Inagaki, Hiroshi, Joh, Takashi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348172/
https://ncbi.nlm.nih.gov/pubmed/25734904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118829
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