Impact of TP53 Codon 72 and MDM2 SNP 309 Polymorphisms in Pancreatic Ductal Adenocarcinoma

Single-nucleotide polymorphisms (SNPs) of TP53 (codon 72, rs1042522) and MDM2 promoter (SNP 309, rs2279744) have been associated with risk for various human cancers. However, studies analyzing these polymorphisms in pancreatic ductal adenocarcinoma (PDAC) are lacking. We investigated TP53 codon 72 a...

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Veröffentlicht in:PLoS One
Hauptverfasser: Hori, Yasuki, Miyabe, Katsuyuki, Yoshida, Michihiro, Nakazawa, Takahiro, Hayashi, Kazuki, Naitoh, Itaru, Shimizu, Shuya, Kondo, Hiromu, Nishi, Yuji, Umemura, Shuichiro, Kato, Akihisa, Ohara, Hirotaka, Inagaki, Hiroshi, Joh, Takashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348172/
https://ncbi.nlm.nih.gov/pubmed/25734904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118829
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