GENE-62. IDENTIFICATION OF FGFR4 p.G388R VARIANT IN CEREBELLAR HEMANGIOBLASTOMAS

di Snuderl, Matija, Kannan, Kasthuri, Gagner, Jean-Pierre, Mashiach, Elad, Karajannis, Matthias, Heguy, Adriana, Zagzag, David
Pubblicato in Neuro Oncol (2019)

GENE-37. ATRX INACTIVATION DISRUPTS GLOBAL HETEROCHROMATIN LANDSCAPES AND ALTERS DISEASE-RELEVANT TRANSCRIPTIONAL ACTIVITY

di Danussi, Carla, Singh, Anand K, Fischer, Grant, Picketts, David J, Kannan, Kasthuri, Rai, Kunal, Huse, Jason T
Pubblicato in Neuro Oncol (2018)

Sindbis Virus with Anti-OX40 Overcomes the Immunosuppressive Tumor Microenvironment of Low-Immunogenic Tumors

di Scherwitzl, Iris, Opp, Silvana, Hurtado, Alicia M., Pampeno, Christine, Loomis, Cynthia, Kannan, Kasthuri, Yu, Minjun, Meruelo, Daniel
Pubblicato in Mol Ther Oncolytics (2020)

Cardiac arrhythmia and neuroexcitability gene variants in resected brain tissue from patients with sudden unexpected death in epilepsy (SUDEP)

di Friedman, Daniel, Kannan, Kasthuri, Faustin, Arline, Shroff, Seema, Thomas, Cheddhi, Heguy, Adriana, Serrano, Jonathan, Snuderl, Matija, Devinsky, Orrin
Pubblicato in NPJ Genom Med (2018)

Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels

di Vaeth, Martin, Wang, Yin-Hu, Eckstein, Miriam, Yang, Jun, Silverman, Gregg J., Lacruz, Rodrigo S., Kannan, Kasthuri, Feske, Stefan
Pubblicato in Nat Commun (2019)

GENE-34. THERAPEUTICALLY TARGETING EPIGENOMIC AND TRANSCRIPTIONAL DYSFUNCTION IN ATRX-DEFICIENT GLIOMA

di Danussi, Carla, Singh, Anand, Pinnamaneni, Pavan, Fisher, Grant, Picketts, David, Kannan, Kasthuri, Rao, Arvind, Rai, Kunal, Huse, Jason
Pubblicato in Neuro Oncol (2019)

CADD-27. G-QUADRUPLEX DNA DRIVES GENOMIC INSTABILITY AND REPRESENTS A TARGETABLE MOLECULAR ABNORMALITY IN ATRX-DEFICIENT MALIGNANT GLIOMA

di Wang, Yuxiang, Yang, Jie, Wu, Wei, Shah, Rachna, Danussi, Carla, Riggins, Gregory, Kannan, Kasthuri, Sulman, Erik, Chan, Timothy, Huse, Jason
Pubblicato in Neuro Oncol (2018)

Remodeling of the Methylation Landscape in Breast Cancer Metastasis

di Reyngold, Marsha, Turcan, Sevin, Giri, Dilip, Kannan, Kasthuri, Walsh, Logan A., Viale, Agnes, Drobnjak, Marija, Vahdat, Linda T., Lee, William, Chan, Timothy A.
Pubblicazione 2014

Whole exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma

di Kannan, Kasthuri, Inagaki, Akiko, Silber, Joachim, Gorovets, Daniel, Zhang, Jianan, Kastenhuber, Edward R., Heguy, Adriana, Petrini, John H., Chan, Timothy A., Huse, Jason T.
Pubblicazione 2012

HG-127 ANAPLASTIC PLEOMORPHIC XANTHOASTROCYTOMAS: A CLINICOPATHOLOGIC AND MOLECULAR PROFILE

di Segal, Devorah, Thomas, Cheddhi, Bowman, Christopher, Kannan, Kasthuri, Wang, Shiyang, Heguy, Adriana, Liechty, Benjamin, Jones, David, Hovestadt, Volker, Pfister, Stefan, Karajannis, Matthias, Snuderl, Matija
Pubblicato in Neuro Oncol (2016)

Nuclear cGMP-Dependent Kinase Regulates Gene Expression via Activity-Dependent Recruitment of a Conserved Histone Deacetylase Complex

di Hao, Yan, Xu, Ningyi, Box, Andrew C., Schaefer, Laura, Kannan, Kasthuri, Zhang, Ying, Florens, Laurence, Seidel, Christopher, Washburn, Michael P., Wiegraebe, Winfried, Mak, Ho Yi
Pubblicazione 2011

Genomic Dissection of Hurthle Cell Carcinoma Reveals a Unique Class of Thyroid Malignancy

di Ganly, Ian, Ricarte Filho, Julio, Eng, Stephanie, Ghossein, Ronald, Morris, Luc G. T., Liang, Yupu, Socci, Nicholas, Kannan, Kasthuri, Mo, Qianxing, Fagin, James A., Chan, Timothy A.
Pubblicato in J Clin Endocrinol Metab (2013)

G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma

di Wang, Yuxiang, Yang, Jie, Wild, Aaron T., Wu, Wei H., Shah, Rachna, Danussi, Carla, Riggins, Gregory J., Kannan, Kasthuri, Sulman, Erik P., Chan, Timothy A., Huse, Jason T.
Pubblicato in Nat Commun (2019)

Transcriptional diversity of long-term glioblastoma survivors

di Gerber, Naamit K., Goenka, Anuj, Turcan, Sevin, Reyngold, Marsha, Makarov, Vladimir, Kannan, Kasthuri, Beal, Kathryn, Omuro, Antonio, Yamada, Yoshiya, Gutin, Phillip, Brennan, Cameron W., Huse, Jason T., Chan, Timothy A.
Pubblicazione 2014

Mitochondrial somatic mutations and the lack of viral genomic variation in recurrent respiratory papillomatosis

di Hao, Yuhan, Ruiz, Ryan, Yang, Liying, Neto, Antonio Galvao, Amin, Milan R., Kelly, Dervla, Achlatis, Stratos, Roof, Scott, Bing, Renjie, Kannan, Kasthuri, Brown, Stuart M., Pei, Zhiheng, Branski, Ryan C.
Pubblicato in Sci Rep (2019)

MB-17 NOVEL CANDIDATE ONCOGENIC DRIVERS IN PINEOBLASTOMA

di Snuderl, Matija, Kannan, Kasthuri, Aminova, Olga, Dolgalev, Igor, Heguy, Adriana, Faustin, Arline, Zagzag, David, Gardner, Sharon, Allen, Jeffrey, Wisoff, Jeffrey, Capper, David, Hovestadt, Volker, Ahsan, Sama, Eberhart, Charles, Pfister, Stefan, Jones, David, Karajannis, Matthias
Pubblicato in Neuro Oncol (2015)

GENO-20 NOVEL CANDIDATE ONCOGENIC DRIVERS IN PINEOBLASTOMA

di Karajannis, Matthias, Kannan, Kasthuri, Aminova, Olga, Dolgalev, Igor, Heguy, Adriana, Faustin, Arline, Zagzag, David, Gardner, Sharon, Allen, Jeffrey, Wisoff, Jeffrey, Capper, David, Hovestadt, Volker, Ahsan, Sama, Eberhart, Charles, Pfister, Stefan, Jones, David, Snuderl, Matija
Pubblicato in Neuro Oncol (2015)

GENE-24. ATRX DEFICIENCY IN GLIOMA CELLS OF ORIGIN PROMOTES DISEASE-DEFINING PHENOTYPES BY WAY OF GLOBAL EPIGENOMIC REMODELING

di Danussi, Carla, Bose, Promita, Parthasarathy, Prasanna, Silberman, Pedro, Van Arnam, John S, Vitucci, Mark, Tang, Oliver, Heguy, Adriana, Chan, Timothy, Sulman, Erik, Lang, Fred, Creighton, Chad J, Deneen, Benjamin, Miller, C Ryan, Picketts, David, Kannan, Kasthuri, Huse, Jason
Pubblicato in Neuro Oncol (2017)

MYC and Twist1 cooperate to drive metastasis by eliciting crosstalk between cancer and innate immunity

di Dhanasekaran, Renumathy, Baylot, Virginie, Kim, Minsoon, Kuruvilla, Sibu, Bellovin, David I, Adeniji, Nia, Rajan KD, Anand, Lai, Ian, Gabay, Meital, Tong, Ling, Krishnan, Maya, Park, Jangho, Hu, Theodore, Barbhuiya, Mustafa A, Gentles, Andrew J, Kannan, Kasthuri, Tran, Phuoc T, Felsher, Dean W
Pubblicato in eLife (2020)

Role of dysregulated cytokine signaling and bacterial triggers in the pathogenesis of Cutaneous T Cell Lymphoma

di Fanok, Melania H., Sun, Amy, Fogli, Laura K., Narendran, Vijay, Eckstein, Miriam, Kannan, Kasthuri, Dolgalev, Igor, Lazaris, Charalampos, Heguy, Adriana, Laird, Mary E., Sundrud, Mark S., Liu, Cynthia, Kutok, Jeff, Lacruz, Rodrigo S., Latkowski, Jo-Ann, Aifantis, Iannis, Ødum, Niels, Hymes, Kenneth B., Goel, Swati, Koralov, Sergei B.
Pubblicato in J Invest Dermatol (2017)