Genomic Dissection of Hurthle Cell Carcinoma Reveals a Unique Class of Thyroid Malignancy

CONTEXT: Hurthle cell cancer (HCC) is an understudied cancer with poor prognosis. OBJECTIVE: Our objective was to elucidate the genomic foundations of HCC. DESIGN AND SETTING: We conducted a large-scale integrated analysis of mutations, gene expression profiles, and copy number alterations in HCC at...

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Pubblicato in:J Clin Endocrinol Metab
Autori principali: Ganly, Ian, Ricarte Filho, Julio, Eng, Stephanie, Ghossein, Ronald, Morris, Luc G. T., Liang, Yupu, Socci, Nicholas, Kannan, Kasthuri, Mo, Qianxing, Fagin, James A., Chan, Timothy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2013
Soggetti:
JCEM Online: Advances in Genetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393465/
https://ncbi.nlm.nih.gov/pubmed/23543667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2012-3539
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