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Immunohistochemical Detection of Mutated BRAF V600E Supports the Clonal Origin of BRAF-Induced Thyroid Cancers Along the Spectrum of Disease Progression
BACKGROUND: The mutated BRAF V600E protein has been specifically detected in papillary thyroid carcinomas (PTCs) using immunohistochemical (IHC) analysis. The clonal origin of PTCs harboring BRAF mutations has recently been called into question. OBJECTIVES: The purpose of this study was 2-fold: (1)...
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| Publicado no: | J Clin Endocrinol Metab |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6287446/ https://ncbi.nlm.nih.gov/pubmed/23775351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-1408 |
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