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Immunohistochemical Detection of Mutated BRAF V600E Supports the Clonal Origin of BRAF-Induced Thyroid Cancers Along the Spectrum of Disease Progression

BACKGROUND: The mutated BRAF V600E protein has been specifically detected in papillary thyroid carcinomas (PTCs) using immunohistochemical (IHC) analysis. The clonal origin of PTCs harboring BRAF mutations has recently been called into question. OBJECTIVES: The purpose of this study was 2-fold: (1)...

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Bibliografische gegevens
Gepubliceerd in:J Clin Endocrinol Metab
Hoofdauteurs: Ghossein, Ronald A., Katabi, Nora, Fagin, James A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287446/
https://ncbi.nlm.nih.gov/pubmed/23775351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-1408
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