Transformation of Mouse Fibroblasts by Jaagsiekte Sheep Retrovirus Envelope Does Not Require Phosphatidylinositol 3-Kinase

par Maeda, Naoyoshi, Inoshima, Yasuo, Fruman, David A., Brachmann, Saskia M., Fan, Hung
Publié 2003

Phosphoinositide 3-Kinase Catalytic Subunit Deletion and Regulatory Subunit Deletion Have Opposite Effects on Insulin Sensitivity in Mice

par Brachmann, Saskia M., Ueki, Kohjiro, Engelman, Jeffrey A., Kahn, Ronald C., Cantley, Lewis C.
Publié 2005

Molecular Balance between the Regulatory and Catalytic Subunits of Phosphoinositide 3-Kinase Regulates Cell Signaling and Survival

par Ueki, Kohjiro, Fruman, David A., Brachmann, Saskia M., Tseng, Yu-Hua, Cantley, Lewis C., Kahn, C. Ronald
Publié 2002

Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1

par Innocenti, Metello, Frittoli, Emanuela, Ponzanelli, Isabella, Falck, John R., Brachmann, Saskia M., Di Fiore, Pier Paolo, Scita, Giorgio
Publié 2003

Increased insulin sensitivity in mice lacking p85β subunit of phosphoinositide 3-kinase

par Ueki, Kohjiro, Yballe, Claudine M., Brachmann, Saskia M., Vicent, David, Watt, John M., Kahn, C. Ronald, Cantley, Lewis C.
Publié 2002

p85 Associates with Unphosphorylated PTEN and the PTEN-Associated Complex

par Rabinovsky, Rosalia, Pochanard, Panisa, McNear, Chontelle, Brachmann, Saskia M., Duke-Cohan, Jonathan S., Garraway, Levi A., Sellers, William R.
Publié 2009

Role of Phosphoinositide 3-Kinase Regulatory Isoforms in Development and Actin Rearrangement

par Brachmann, Saskia M., Yballe, Claudine M., Innocenti, Metello, Deane, Jonathan A., Fruman, David A., Thomas, Sheila M., Cantley, Lewis C.
Publié 2005

Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells

par Brachmann, Saskia M., Hofmann, Irmgard, Schnell, Christian, Fritsch, Christine, Wee, Susan, Lane, Heidi, Wang, Shaowen, Garcia-Echeverria, Carlos, Maira, Sauveur-Michel
Publié 2009

Accepting from the best donor; analysis of long-lifetime donor fluorescent protein pairings to optimise dynamic FLIM-based FRET experiments

par Martin, Kirsty J., McGhee, Ewan J., Schwarz, Juliana P., Drysdale, Martin, Brachmann, Saskia M., Stucke, Volker, Sansom, Owen J., Anderson, Kurt I.
Publié dans PLoS One (2018)

Dual Regulatory Roles of the Phosphatidylinositol 3-Kinase In Interferon Signaling

par Kaur, Surinder, Sassano, Antonella, Joseph, Ajith M, Majchrzak-Kita, Beata, Eklund, Elizabeth A., Verma, Amit, Brachmann, Saskia M., Fish, Eleanor N., Platanias, Leonidas C.
Publié 2008

Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

par Vieira, Otilia V., Botelho, Roberto J., Rameh, Lucia, Brachmann, Saskia M., Matsuo, Tsuyoshi, Davidson, Howard W., Schreiber, Alan, Backer, Jonathan M., Cantley, Lewis C., Grinstein, Sergio
Publié 2001

Genetic heterogeneity and clonal evolution during metastasis in breast cancer patient-derived tumor xenograft models

par Sprouffske, Kathleen, Kerr, Grainne, Li, Cheng, Prahallad, Anirudh, Rebmann, Ramona, Waehle, Verena, Naumann, Ulrike, Bitter, Hans, Jensen, Michael R, Hofmann, Francesco, Brachmann, Saskia M, Ferretti, Stéphane, Kauffmann, Audrey
Publié dans Comput Struct Biotechnol J (2020)

K-RAS Mutant Pancreatic Tumors Show Higher Sensitivity to MEK than to PI3K Inhibition In Vivo

par Hofmann, Irmgard, Weiss, Andreas, Elain, Gaelle, Schwaederle, Maria, Sterker, Dario, Romanet, Vincent, Schmelzle, Tobias, Lai, Albert, Brachmann, Saskia M., Bentires-Alj, Mohamed, Roberts, Thomas M., Sellers, William R., Hofmann, Francesco, Maira, Sauveur-Michel
Publié 2012

Identification of Elongation Factor G as the Conserved Cellular Target of Argyrin B

par Nyfeler, Beat, Hoepfner, Dominic, Palestrant, Deborah, Kirby, Christina A., Whitehead, Lewis, Yu, Robert, Deng, Gejing, Caughlan, Ruth E., Woods, Angela L., Jones, Adriana K., Barnes, S. Whitney, Walker, John R., Gaulis, Swann, Hauy, Ervan, Brachmann, Saskia M., Krastel, Philipp, Studer, Christian, Riedl, Ralph, Estoppey, David, Aust, Thomas, Movva, N. Rao, Wang, Zuncai, Salcius, Michael, Michaud, Gregory A., McAllister, Gregory, Murphy, Leon O., Tallarico, John A., Wilson, Christopher J., Dean, Charles R.
Publié 2012

A RAC-GEF network critical for early intestinal tumourigenesis

par Pickering, K. A., Gilroy, K., Cassidy, J. W., Fey, S. K., Najumudeen, A. K., Zeiger, L. B., Vincent, D. F., Gay, D. M., Johansson, J., Fordham, R. P., Miller, B., Clark, W., Hedley, A., Unal, E. B., Kiel, C., McGhee, E., Machesky, L. M., Nixon, C., Johnsson, A. E., Bain, M., Strathdee, D., van Hoof, S. R., Medema, J. P., Anderson, K. I., Brachmann, S. M., Stucke, V. M., Malliri, A., Drysdale, M., Turner, M., Serrano, L., Myant, K., Campbell, A. D., Sansom, O. J.
Publié dans Nat Commun (2021)