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Increased insulin sensitivity in mice lacking p85β subunit of phosphoinositide 3-kinase
On the basis of ex vivo studies using insulin-responsive cells, activation of a Class IA phosphoinositide 3-kinase (PI3K) seems to be required for a wide variety of cellular responses downstream of insulin. The Class IA PI3K enzymes are heterodimers of catalytic and regulatory subunits. In mammals,...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC117575/ https://ncbi.nlm.nih.gov/pubmed/11752399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012581799 |
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