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Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85α subunit

Proteins such as the product of the breakpoint cluster region, chimaerin, and the Src homology 3-binding protein 3BP1, are GTPase activating proteins (GAPs) for members of the Rho subfamily of small GTP-binding proteins (G proteins or GTPases). A 200-residue region, named the breakpoint cluster regi...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Musacchio, Andrea, Cantley, Lewis C., Harrison, Stephen C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1996
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26139/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8962058/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.25.14373
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