Increased insulin sensitivity in mice lacking p85β subunit of phosphoinositide 3-kinase

On the basis of ex vivo studies using insulin-responsive cells, activation of a Class IA phosphoinositide 3-kinase (PI3K) seems to be required for a wide variety of cellular responses downstream of insulin. The Class IA PI3K enzymes are heterodimers of catalytic and regulatory subunits. In mammals,...

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出版年:	Proc Natl Acad Sci U S A
主要な著者:	Ueki, Kohjiro, Yballe, Claudine M., Brachmann, Saskia M., Vicent, David, Watt, John M., Kahn, C. Ronald, Cantley, Lewis C.
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 2001
主題:	Biological Sciences
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117575/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11752399/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.012581799
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