Cargando...
A RAC-GEF network critical for early intestinal tumourigenesis
RAC1 activity is critical for intestinal homeostasis, and is required for hyperproliferation driven by loss of the tumour suppressor gene Apc in the murine intestine. To avoid the impact of direct targeting upon homeostasis, we reasoned that indirect targeting of RAC1 via RAC-GEFs might be effective...
Guardado en:
Publicado en: | Nat Commun |
---|---|
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7782582/ https://ncbi.nlm.nih.gov/pubmed/33397922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20255-4 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|