Loss of N‐WASP drives early progression in an Apc model of intestinal tumourigenesis

N‐WASP (WASL) is a widely expressed cytoskeletal signalling and scaffold protein also implicated in regulation of Wnt signalling and homeostatic maintenance of skin epithelial architecture. N‐WASP mediates invasion of cancer cells in vitro and its depletion reduces invasion and metastatic disseminat...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Morris, Hayley T, Fort, Loic, Spence, Heather J, Patel, Rachana, Vincent, David F, Park, James H, Snapper, Scott B, Carey, Francis A, Sansom, Owen J, Machesky, Laura M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2018
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033012/
https://ncbi.nlm.nih.gov/pubmed/29672847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5086
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