Loss of N‐WASP drives early progression in an Apc model of intestinal tumourigenesis

N‐WASP (WASL) is a widely expressed cytoskeletal signalling and scaffold protein also implicated in regulation of Wnt signalling and homeostatic maintenance of skin epithelial architecture. N‐WASP mediates invasion of cancer cells in vitro and its depletion reduces invasion and metastatic disseminat...

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Dettagli Bibliografici
Pubblicato in:J Pathol
Autori principali: Morris, Hayley T, Fort, Loic, Spence, Heather J, Patel, Rachana, Vincent, David F, Park, James H, Snapper, Scott B, Carey, Francis A, Sansom, Owen J, Machesky, Laura M
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2018
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Original Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033012/
https://ncbi.nlm.nih.gov/pubmed/29672847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5086
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