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Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis
Mutations in the Ras family of proteins (predominantly in H-Ras) occur in approximately 40% of urothelial cell carcinoma (UCC). However, relatively little is known about subsequent mutations/pathway alterations that allow tumour progression. Indeed, expressing mutant H-Ras within the mouse bladder d...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101820/ https://ncbi.nlm.nih.gov/pubmed/21368895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.7 |
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