ERK activation drives intestinal tumorigenesis in Apc(min/)(+) mice

TLR signaling is essential for intestinal tumorigenesis in Apc(min/)(+) mice, but the mechanisms by which this protein enhances tumor growth are unknown. Here we show that the Microflora-MyD88-ERK signaling in intestinal epithelial cells (IEC) promotes tumorigenesis by increasing the stability of th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lee, Sung Hee, Hu, Li-Li, Gonzalez-Navajas, Jose, Seo, Geom Seog, Shen, Carol, Brick, Jonathan, Herdman, Scott, Varki, Nissi, Corr, Maripat, Lee, Jongdae, Raz, Eyal
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882530/
https://ncbi.nlm.nih.gov/pubmed/20473309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2143
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados