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Deficiency of SPARC suppresses intestinal tumorigenesis in APC(Min/+) mice
BACKGROUND AND AIMS: SPARC (secreted protein acidic, rich in cysteine) is a matricellular protein that has been found to be activated in a number of human cancers. More recently, it has been shown to be upregulated in human gastric and colorectal cancer. We therefore wished to address the functional...
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Главные авторы: | , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
BMJ Group
2007
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2000234/ https://ncbi.nlm.nih.gov/pubmed/17299058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.116921 |
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