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Loss of Rassf1a co-operates with Apc(Min) to accelerate intestinal tumourigenesis
Promoter methylation of the RAS-association domain family 1, isoform A gene (RASSF1A) is one of the most frequent events found in human tumours. In this study we set out to test the hypothesis that loss of Rassf1a can co-operate with inactivation of the adenomatous polyposis coli (Apc) gene to accel...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3706934/ https://ncbi.nlm.nih.gov/pubmed/18391979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.94 |
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