Loss of Rassf1a co-operates with Apc(Min) to accelerate intestinal tumourigenesis

Promoter methylation of the RAS-association domain family 1, isoform A gene (RASSF1A) is one of the most frequent events found in human tumours. In this study we set out to test the hypothesis that loss of Rassf1a can co-operate with inactivation of the adenomatous polyposis coli (Apc) gene to accel...

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Hlavní autoři: van der Weyden, L., Arends, M.J., Dovey, O.M., Harrison, H. L., Lefebvre, G., Conte, N., Gergely, F.V., Bradley, A., Adams, D.J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706934/
https://ncbi.nlm.nih.gov/pubmed/18391979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.94
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