RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways

Current therapeutic options for treating colorectal cancer have little clinical efficacy and acquired resistance during treatment is common, even following patient stratification. Understanding the mechanisms that promote therapy resistance may lead to the development of novel therapeutic options th...

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Publicado en:Nat Commun
Autores principales: Gudiño, Victoria, Pohl, Sebastian Öther-Gee, Billard, Caroline V., Cammareri, Patrizia, Bolado, Alfonso, Aitken, Stuart, Stevenson, David, Hall, Adam E., Agostino, Mark, Cassidy, John, Nixon, Colin, von Kriegsheim, Alex, Freile, Paz, Popplewell, Linda, Dickson, George, Murphy, Laura, Wheeler, Ann, Dunlop, Malcolm, Din, Farhat, Strathdee, Douglas, Sansom, Owen J., Myant, Kevin B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058071/
https://ncbi.nlm.nih.gov/pubmed/33879799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22531-3
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