Expression of the Human FSHD-Linked DUX4 Gene Induces Neurogenesis During Differentiation of Murine Embryonic Stem Cells

Por Dandapat, Abhijit, Hartweck, Lynn M., Bosnakovski, Darko, Kyba, Michael
Publicado em 2013

Dux facilitates post-implantation development, but is not essential for zygotic genome activation

Por Bosnakovski, Darko, Gearhart, Micah D, Ho Choi, Si, Kyba, Michael
Publicado no Biol Reprod (2020)

Comment on Structural basis of DUX4/IGH-driven transactivation

Por Aihara, Hideki, Shi, Ke, Lee, John K., Bosnakovski, Darko, Kyba, Michael
Publicado no Leukemia (2018)

Biphasic Myopathic Phenotype of Mouse DUX, an ORF within Conserved FSHD-Related Repeats

Por Bosnakovski, Darko, Daughters, Randy S., Xu, Zhaohui, Slack, Jonathan M. W., Kyba, Michael
Publicado em 2009

Functional Myogenic Engraftment from Mouse iPS Cells

Por Darabi, Radbod, Pan, Weihong, Bosnakovski, Darko, Baik, June, Kyba, Michael, Perlingeiro, Rita C. R.
Publicado no Stem Cell Rev (2011)

Low level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression

Por Bosnakovski, Darko, Gearhart, Micah D., Toso, Erik A., Ener, Elizabeth T., Choi, Si Ho, Kyba, Michael
Publicado no Sci Rep (2018)

Decreased Proliferation Kinetics of Mouse Myoblasts Overexpressing FRG1

Por Chen, Steven C., Frett, Ellie, Marx, Joseph, Bosnakovski, Darko, Reed, Xylena, Kyba, Michael, Kennedy, Brian K.
Publicado em 2011

High-throughput screening identifies inhibitors of DUX4-induced myoblast toxicity

Por Bosnakovski, Darko, Choi, Si Ho, Strasser, Jessica M, Toso, Erik A, Walters, Michael A, Kyba, Michael
Publicado em 2014

Prospective Isolation of Skeletal Muscle Stem Cells with a Pax7 Reporter

Por BOSNAKOVSKI, DARKO, XU, ZHAOHUI, LI, WEI, THET, SUWANNEE, CLEAVER, ONDINE, PERLINGEIRO, RITA C.R., KYBA, MICHAEL
Publicado no Stem Cells (2008)

DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes

Por Choi, Si Ho, Gearhart, Micah D., Cui, Ziyou, Bosnakovski, Darko, Kim, Minjee, Schennum, Natalie, Kyba, Michael
Publicado no Nucleic Acids Res (2016)

Transcriptional inhibitors identified in a 160,000-compound small molecule DUX4-viability screen

Por Choi, Si Ho, Bosnakovski, Darko, Strasser, Jessica M., Toso, Erik A., Walters, Michael A., Kyba, Michael
Publicado no J Biomol Screen (2016)

Inducible cassette exchange: a rapid and efficient system enabling conditional gene expression in embryonic stem and primary cells

Por Iacovino, Michelina, Bosnakovski, Darko, Fey, Holger, Rux, Danielle, Bajwa, Gagan, Mahen, Elisabeth, Mitanoska, Ana, Xu, Zhaohui, Kyba, Michael
Publicado em 2011

White Fat Progenitors Reside in the Adipose Vasculature

Por Tang, Wei, Zeve, Daniel, Suh, Jae Myoung, Bosnakovski, Darko, Kyba, Michael, Hammer, Robert E., Tallquist, Michelle D., Graff, Jonathan M.
Publicado em 2008

p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy

Por Bosnakovski, Darko, Gearhart, Micah D., Toso, Erik A., Recht, Olivia O., Cucak, Anja, Jain, Abhinav K., Barton, Michelle C., Kyba, Michael
Publicado no Dis Model Mech (2017)

Muscle pathology from stochastic low level DUX4 expression in an FSHD mouse model

Por Bosnakovski, Darko, Chan, Sunny S. K., Recht, Olivia O., Hartweck, Lynn M., Gustafson, Collin J., Athman, Laura L., Lowe, Dawn A., Kyba, Michael
Publicado no Nat Commun (2017)

Author Correction: Muscle pathology from stochastic low level DUX4 expression in an FSHD mouse model

Por Bosnakovski, Darko, Chan, Sunny S. K., Recht, Olivia O., Hartweck, Lynn M., Gustafson, Collin J., Athman, Laura L., Lowe, Dawn A., Kyba, Michael
Publicado no Nat Commun (2018)

Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA

Por Lee, John K., Bosnakovski, Darko, Toso, Erik A., Dinh, Tracy, Banerjee, Surajit, Bohl, Thomas E., Shi, Ke, Orellana, Kayo, Kyba, Michael, Aihara, Hideki
Publicado no Cell Rep (2018)

A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death

Por Bosnakovski, Darko, da Silva, Meiricris T., Sunny, Sithara T., Ener, Elizabeth T., Toso, Erik A., Yuan, Ce, Cui, Ziyou, Walters, Michael A., Jadhav, Ajit, Kyba, Michael
Publicado no Sci Adv (2019)

The DUX4 homeodomains mediate inhibition of myogenesis and are functionally exchangeable with the Pax7 homeodomain

Por Bosnakovski, Darko, Toso, Erik A., Hartweck, Lynn M., Magli, Alessandro, Lee, Heather A., Thompson, Eliza R., Dandapat, Abhijit, Perlingeiro, Rita C. R., Kyba, Michael
Publicado no J Cell Sci (2017)

Transcriptional and cytopathological hallmarks of FSHD in chronic DUX4-expressing mice

Por Bosnakovski, Darko, Shams, Ahmed S., Yuan, Ce, da Silva, Meiricris T., Ener, Elizabeth T., Baumann, Cory W., Lindsay, Angus J., Verma, Mayank, Asakura, Atsushi, Lowe, Dawn A., Kyba, Michael
Publicado no J Clin Invest (2020)