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p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy
Facioscapulohumeral muscular dystrophy (FSHD) is a genetically dominant myopathy caused by mutations that disrupt repression of the normally silent DUX4 gene, which encodes a transcription factor that has been shown to interfere with myogenesis when misexpressed at very low levels in myoblasts and t...
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| Publicado no: | Dis Model Mech |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5665455/ https://ncbi.nlm.nih.gov/pubmed/28754837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.030064 |
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