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The prospects of targeting DUX4 in facioscapulohumeral muscular dystrophy

PURPOSE OF REVIEW: Facioscapulohumeral muscular dystrophy (FSHD) is a neuromuscular disorder that is caused by incomplete repression of the transcription factor DUX4 in skeletal muscle. To date, there is no DUX4-targeting treatment to prevent or delay disease progression. In this review, we summariz...

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Detalhes bibliográficos
Publicado no:Curr Opin Neurol
Main Authors: Bouwman, Linde F., van der Maarel, Silvère M., de Greef, Jessica C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735392/
https://ncbi.nlm.nih.gov/pubmed/32796277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WCO.0000000000000849
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