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Epigenetic Mechanisms of Facioscapulohumeral Muscular Dystrophy

Facioscapulohumeral muscular dystrophy (FSHD) seems to be caused by a complex epigenetic disease mechanism as a result of contraction of the polymorphic macrosatellite repeat D4Z4 on chromosome 4qter. Currently, the exact mechanism causing the FSHD phenotype is still not elucidated. In this review,...

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Detalhes bibliográficos
Main Authors: de Greef, Jessica C., Frants, Rune R., van der Maarel, Silvère M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650037/
https://ncbi.nlm.nih.gov/pubmed/18723032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2008.07.011
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