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Low level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression
Loss of silencing of the DUX4 gene on chromosome 4 causes facioscapulohumeral muscular dystrophy. While high level DUX4 expression induces apoptosis, the effects of low level DUX4 expression on human myogenic cells are not well understood. Low levels and sporadic expression of DUX4 have been reporte...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6240038/ https://ncbi.nlm.nih.gov/pubmed/30446688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35150-8 |
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