Transcriptional and cytopathological hallmarks of FSHD in chronic DUX4-expressing mice

Facioscapulohumeral muscular dystrophy (FSHD) is caused by loss of repression of the DUX4 gene; however, the DUX4 protein is rare and difficult to detect in human muscle biopsies, and pathological mechanisms are obscure. FSHD is also a chronic disease that progresses slowly over decades. We used the...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Bosnakovski, Darko, Shams, Ahmed S., Yuan, Ce, da Silva, Meiricris T., Ener, Elizabeth T., Baumann, Cory W., Lindsay, Angus J., Verma, Mayank, Asakura, Atsushi, Lowe, Dawn A., Kyba, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190912/
https://ncbi.nlm.nih.gov/pubmed/32250341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133303
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