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Expression of the Human FSHD-Linked DUX4 Gene Induces Neurogenesis During Differentiation of Murine Embryonic Stem Cells

Misexpression of the double homeodomain protein DUX4 in muscle is believed to cause facioscapulohumeral muscular dystrophy (FSHD). Although strategies are being devised to inhibit DUX4 activity in FSHD, there is little known about the normal function of this protein. Expression of DUX4 has been repo...

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Bibliografske podrobnosti
Main Authors: Dandapat, Abhijit, Hartweck, Lynn M., Bosnakovski, Darko, Kyba, Michael
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749711/
https://ncbi.nlm.nih.gov/pubmed/23560660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0643
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