NF-κB Signaling: Multiple angles to target OA

Por Marcu, Kenneth B., Otero, Miguel, Olivotto, Eleonora, Borzi, Rosa Maria, Goldring, Mary B.
Publicado em 2010

Lithium Chloride Dependent Glycogen Synthase Kinase 3 Inactivation Links Oxidative DNA Damage, Hypertrophy and Senescence in Human Articular Chondrocytes and Reproduces Chondrocyte...

Por Guidotti, Serena, Minguzzi, Manuela, Platano, Daniela, Cattini, Luca, Trisolino, Giovanni, Mariani, Erminia, Borzì, Rosa Maria
Publicado no PLoS One (2015)

Hydroxytyrosol Prevents Increase of Osteoarthritis Markers in Human Chondrocytes Treated with Hydrogen Peroxide or Growth-Related Oncogene α

Por Facchini, Annalisa, Cetrullo, Silvia, D'Adamo, Stefania, Guidotti, Serena, Minguzzi, Manuela, Facchini, Andrea, Borzì, Rosa Maria, Flamigni, Flavio
Publicado em 2014

Polyamine Depletion Inhibits NF-κB Binding to DNA and Interleukin-8 production in Human Chondrocytes Stimulated by Tumor Necrosis Factor-α

Por FACCHINI, ANNALISA, BORZÌ, ROSA MARIA, MARCU, KENNETH B., STEFANELLI, CLAUDIO, OLIVOTTO, ELEONORA, GOLDRING, MARY B., FACCHINI, ANDREA, FLAMIGNI, FLAVIO
Publicado em 2005

Sustained NF-κB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1

Por Penzo, Marianna, Massa, Paul E., Olivotto, Eleonora, Bianchi, Francesca, Borzi, Rosa Maria, Hanidu, Adedayo, Li, Xiang, Li, Jun, Marcu, Kenneth B.
Publicado em 2009

Human Osteoarthritic Cartilage Shows Reduced In Vivo Expression of IL-4, a Chondroprotective Cytokine that Differentially Modulates IL-1β-Stimulated Production of Chemokines and Ma...

Por Assirelli, Elisa, Pulsatelli, Lia, Dolzani, Paolo, Platano, Daniela, Olivotto, Eleonora, Filardo, Giuseppe, Trisolino, Giovanni, Facchini, Andrea, Borzì, Rosa Maria, Meliconi, Riccardo
Publicado em 2014

IKKα/CHUK Regulates Extracellular Matrix Remodeling Independent of Its Kinase Activity to Facilitate Articular Chondrocyte Differentiation

Por Olivotto, Eleonora, Otero, Miguel, Astolfi, Annalisa, Platano, Daniela, Facchini, Annalisa, Pagani, Stefania, Flamigni, Flavio, Facchini, Andrea, Goldring, Mary B., Borzì, Rosa Maria, Marcu, Kenneth B.
Publicado em 2013

Differential requirements for IKKα and IKKβ in the differentiation of primary human osteoarthritic chondrocytes

Por Olivotto, Eleonora, Borzi', Rosa Maria, Vitellozzi, Roberta, Pagani, Stefania, Facchini, Annalisa, Battistelli, Michela, Penzo, Marianna, Li, Xiang, Flamigni, Flavio, Li, Jun, Falcieri, Elisabetta, Facchini, Andrea, Marcu, Kenneth B
Publicado em 2008

ROLES OF INFLAMMATORY AND ANABOLIC CYTOKINES IN CARTILAGE METABOLISM: SIGNALS AND MULTIPLE EFFECTORS CONVERGE UPON MMP-13 REGULATION IN OSTEOARTHRITIS

Por Goldring, Mary B., Otero, Miguel, Plumb, Darren A., Dragomir, Cecilia, Favero, Marta, El Hachem, Karim, Hashimoto, Ko, Roach, Helmtrud I., Olivotto, Eleonora, Borzì, Rosa Maria, Marcu, Kenneth B.
Publicado em 2011

p16(INK4a) and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis

Por Philipot, Didier, Guérit, David, Platano, Daniela, Chuchana, Paul, Olivotto, Eleonora, Espinoza, Francisco, Dorandeu, Anne, Pers, Yves-Marie, Piette, Jacques, Borzi, Rosa Maria, Jorgensen, Christian, Noel, Danièle, Brondello, Jean-Marc
Publicado em 2014

MMP-13 loss associated with impaired ECM remodelling disrupts chondrocyte differentiation by concerted effects on multiple regulatory factors

Por Borzi, Rosa Maria, Olivotto, Eleonora, Pagani, Stefania, Vitellozzi, Roberta, Neri, Simona, Battistelli, Michela, Falcieri, Elisabetta, Facchini, Annalisa, Flamigni, Flavio, Penzo, Marianna, Platano, Daniela, Santi, Spartaco, Facchini, Andrea, Marcu, Kenneth B
Publicado em 2010