Human Osteoarthritic Cartilage Shows Reduced In Vivo Expression of IL-4, a Chondroprotective Cytokine that Differentially Modulates IL-1β-Stimulated Production of Chemokines and Matrix-Degrading Enzymes In Vitro

BACKGROUND: In osteoarthritis (OA), an inflammatory environment is responsible for the imbalance between the anabolic and catabolic activity of chondrocytes and, thus, for articular cartilage derangement. This study was aimed at providing further insight into the impairment of the anabolic cytokine...

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Detalhes bibliográficos
Main Authors: Assirelli, Elisa, Pulsatelli, Lia, Dolzani, Paolo, Platano, Daniela, Olivotto, Eleonora, Filardo, Giuseppe, Trisolino, Giovanni, Facchini, Andrea, Borzì, Rosa Maria, Meliconi, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018406/
https://ncbi.nlm.nih.gov/pubmed/24819779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096925
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