Bone-metabolic functions and modulators

Por Bronner, Felix, Farach-Carson, Mary C, Roach, Helmtrud I
Publicado em 2012

Epigenetic aspects of chronic diseases

Por Roach, Helmtrud I., Bronner, Felix, Oreffo, Richard O.C.
Publicado em 2011

DNA De-methylation at Specific CpG Sites in the IL1B Promoter in Response to Inflammatory Cytokines in Human Articular Chondrocytes

Por Hashimoto, Ko, Oreffo, Richard O.C., Gibson, Marc B., Goldring, Mary B., Roach, Helmtrud I.
Publicado em 2009

Epigenetic Regulation during Fetal Femur Development: DNA Methylation Matters

Por de Andrés, María C., Kingham, Emmajayne, Imagawa, Kei, Gonzalez, Antonio, Roach, Helmtrud I., Wilson, David I., Oreffo, Richard O. C.
Publicado em 2013

Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis

Por de Andrés, María C., Imagawa, Kei, Hashimoto, Ko, Gonzalez, Antonio, Goldring, Mary B., Roach, Helmtrud I., Oreffo, Richard O.C.
Publicado em 2011

Loss of Methylation in CpG Sites in the NF-κB Enhancer Elements of Inducible Nitric Oxide Synthase Is Responsible for Gene Induction in Human Articular Chondrocytes

Por de Andrés, María C., Imagawa, Kei, Hashimoto, Ko, Gonzalez, Antonio, Roach, Helmtrud I., Goldring, Mary B., Oreffo, Richard O. C.
Publicado em 2013

The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes – Implications for osteoarthritis

Por Imagawa, Kei, de Andrés, MC, Hashimoto, Ko, Pitt, Dominic, Itoi, Eiji, Goldring, Mary B., Roach, Helmtrud I., Oreffo, Richard O.C.
Publicado em 2011

Association of Reduced Type IX Collagen Gene Expression in Human Osteoarthritic Chondrocytes With Epigenetic Silencing by DNA Hypermethylation

Por Imagawa, Kei, de Andrés, María C, Hashimoto, Ko, Itoi, Eiji, Otero, Miguel, Roach, Helmtrud I, Goldring, Mary B, Oreffo, Richard O C
Publicado em 2014

Regulated Transcription of Human Matrix Metalloproteinase 13 (MMP13) and Interleukin-1β (IL1B) Genes in Chondrocytes Depends on Methylation of Specific Proximal Promoter CpG Sites

Por Hashimoto, Ko, Otero, Miguel, Imagawa, Kei, de Andrés, María C., Coico, Jonathan M., Roach, Helmtrud I., Oreffo, Richard O. C., Marcu, Kenneth B., Goldring, Mary B.
Publicado em 2013

ROLES OF INFLAMMATORY AND ANABOLIC CYTOKINES IN CARTILAGE METABOLISM: SIGNALS AND MULTIPLE EFFECTORS CONVERGE UPON MMP-13 REGULATION IN OSTEOARTHRITIS

Por Goldring, Mary B., Otero, Miguel, Plumb, Darren A., Dragomir, Cecilia, Favero, Marta, El Hachem, Karim, Hashimoto, Ko, Roach, Helmtrud I., Olivotto, Eleonora, Borzì, Rosa Maria, Marcu, Kenneth B.
Publicado em 2011