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Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis

OBJECTIVES: Suppressor of cytokine signalling (SOCS) proteins are inhibitors of cytokine signalling that function via the JAK/STAT pathway (Janus kinase/signal transducers and activators of transcription). Eight SOCS proteins, SOCS1–SOCS7 and CIS-1 (cytokine-inducible SH2-domain, with similar struct...

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Bibliografiska uppgifter
Huvudupphovsmän: de Andrés, María C., Imagawa, Kei, Hashimoto, Ko, Gonzalez, Antonio, Goldring, Mary B., Roach, Helmtrud I., Oreffo, Richard O.C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937865/
https://ncbi.nlm.nih.gov/pubmed/21352802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.02.101
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