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DNA De-methylation at Specific CpG Sites in the IL1B Promoter in Response to Inflammatory Cytokines in Human Articular Chondrocytes
OBJECTIVE: To determine whether changes in the DNA methylation status in the promoter region of the gene encoding interleukin-1β (IL-1β) account for expression of IL1B mRNA after long-term treatment of human articular chondrocytes with inflammatory cytokines. METHODS: IL-1β or TNFα combined with onc...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788707/ https://ncbi.nlm.nih.gov/pubmed/19877066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24882 |
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