ROLES OF INFLAMMATORY AND ANABOLIC CYTOKINES IN CARTILAGE METABOLISM: SIGNALS AND MULTIPLE EFFECTORS CONVERGE UPON MMP-13 REGULATION IN OSTEOARTHRITIS

Human cartilage is a complex tissue of matrix proteins that vary in amount and orientation from superficial to deep layers and from loaded to unloaded zones. A major challenge to efforts to repair cartilage by stem cell-based and other tissue engineering strategies is the inability of the resident c...

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Main Authors: Goldring, Mary B., Otero, Miguel, Plumb, Darren A., Dragomir, Cecilia, Favero, Marta, El Hachem, Karim, Hashimoto, Ko, Roach, Helmtrud I., Olivotto, Eleonora, Borzì, Rosa Maria, Marcu, Kenneth B.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937960/
https://ncbi.nlm.nih.gov/pubmed/21351054
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