Polyamine Depletion Inhibits NF-κB Binding to DNA and Interleukin-8 production in Human Chondrocytes Stimulated by Tumor Necrosis Factor-α

The activation of the NF-κB pathway by pro-inflammatory cytokines, such as tumor necrosis factor-α (TNFα), can be an important contributor for the re-programming of chondrocyte gene expression, thereby making it a therapeutic target in articular diseases. To search for new approaches to limit cartil...

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Main Authors: FACCHINI, ANNALISA, BORZÌ, ROSA MARIA, MARCU, KENNETH B., STEFANELLI, CLAUDIO, OLIVOTTO, ELEONORA, GOLDRING, MARY B., FACCHINI, ANDREA, FLAMIGNI, FLAVIO
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1226412/
https://ncbi.nlm.nih.gov/pubmed/15828019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.20368
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