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Differential requirements for IKKα and IKKβ in the differentiation of primary human osteoarthritic chondrocytes
OBJECTIVE: Osteoarthritic chondrocytes behave in an intrinsically de-regulated manner characterized by the chronic loss of healthy cartilage and inappropriate differentiation to a hypertrophic-like state. IKKβ and IKKα are essential kinases that activate NF-κB transcription factors, which regulate c...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927097/ https://ncbi.nlm.nih.gov/pubmed/18163512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23211 |
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