Differential requirements for IKKα and IKKβ in the differentiation of primary human osteoarthritic chondrocytes

OBJECTIVE: Osteoarthritic chondrocytes behave in an intrinsically de-regulated manner characterized by the chronic loss of healthy cartilage and inappropriate differentiation to a hypertrophic-like state. IKKβ and IKKα are essential kinases that activate NF-κB transcription factors, which regulate c...

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Main Authors: Olivotto, Eleonora, Borzi', Rosa Maria, Vitellozzi, Roberta, Pagani, Stefania, Facchini, Annalisa, Battistelli, Michela, Penzo, Marianna, Li, Xiang, Flamigni, Flavio, Li, Jun, Falcieri, Elisabetta, Facchini, Andrea, Marcu, Kenneth B
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927097/
https://ncbi.nlm.nih.gov/pubmed/18163512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23211
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