RACK1 and β-arrestin2 attenuate dimerization of PDE4 cAMP phosphodiesterase PDE4D5

Por Bolger, Graeme B.
Publicado no Cell Signal (2015)

The RNA-binding protein SERBP1 interacts selectively with the signaling protein RACK1

Por Bolger, Graeme B.
Publicado no Cell Signal (2017)

Delineation of RAID1, the RACK1 interaction domain located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5

Por Bolger, Graeme B, McCahill, Angela, Yarwood, Stephen J, Steele, Michael R, Warwicker, Jim, Houslay, Miles D
Publicado em 2002

Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F4...

Por MacKenzie, Simon J., Yarwood, Stephen J., Peden, Alexander H., Bolger, Graeme B., Vernon, Richard G., Houslay, Miles D.
Publicado em 1998

Interaction between LIS1 and PDE4, and its role in cytoplasmic dynein function

Por Murdoch, Hannah, Vadrevu, Suryakiran, Prinz, Anke, Dunlop, Allan J., Klussmann, Enno, Bolger, Graeme B., Norman, James C., Houslay, Miles D.
Publicado em 2011

Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domains

Por Bolger, Graeme B., Dunlop, Allan J., Meng, Dong, Day, Jon P., Klussmann, Enno, Baillie, George S., Adams, David R., Houslay, Miles D.
Publicado no Cell Signal (2015)

Molecular cloning and subcellular distribution of the novel PDE4B4 cAMP-specific phosphodiesterase isoform.

Por Shepherd, Malcolm, McSorley, Theresa, Olsen, Aileen E, Johnston, Lee Ann, Thomson, Neil C, Baillie, George S, Houslay, Miles D, Bolger, Graeme B
Publicado em 2003

cAMP-specific PDE4 Phosphodiesterases and AIP in the Pathogenesis of Pituitary Tumors

Por Bolger, Graeme B., Bizzi, Mariana Ferreira, Brant Pinheiro, Sergio Veloso, Trivellin, Giampaolo, Smoot, Lisa, Accavitti, Mary-Ann, Korbonits, Márta, Ribeiro-Oliveira, Antonio
Publicado no Endocr Relat Cancer (2016)

Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of β-arrestin using spot-immobilized peptide arrays

Por Baillie, George S., Adams, David R., Bhari, Narinder, Houslay, Thomas M., Vadrevu, Suryakiran, Meng, Dong, Li, Xiang, Dunlop, Allan, Milligan, Graeme, Bolger, Graeme B., Klussmann, Enno, Houslay, Miles D.
Publicado em 2007

Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, β-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5

Por Bolger, Graeme B., Baillie, George S., Li, Xiang, Lynch, Martin J., Herzyk, Pawel, Mohamed, Ahmed, High Mitchell, Lisa, McCahill, Angela, Hundsrucker, Christian, Klussmann, Enno, Adams, David R., Houslay, Miles D.
Publicado em 2006

Regulatory domain phosphorylation to distinguish the mechanistic basis underlying acute CFTR modulators

Por Pyle, Louise C., Ehrhardt, Annette, Mitchell, Lisa High, Fan, LiJuan, Ren, Aixia, Naren, Anjaparavanda P., Li, Yao, Clancy, J. P., Bolger, Graeme B., Sorscher, Eric J., Rowe, Steven M.
Publicado em 2011

Characterization of Aryl Hydrocarbon Receptor Interacting Protein (AIP) Mutations in Familial Isolated Pituitary Adenoma Families

Por Igreja, Susana, Chahal, Harvinder S, King, Peter, Bolger, Graeme B, Srirangalingam, Umasuthan, Guasti, Leonardo, Chapple, J Paul, Trivellin, Giampaolo, Gueorguiev, Maria, Guegan, Katie, Stals, Karen, Khoo, Bernard, Kumar, Ajith V, Ellard, Sian, Grossman, Ashley B, Korbonits, Márta
Publicado em 2010

Cystic Fibrosis Transmembrane Conductance Regulator Activation by Roflumilast Contributes to Therapeutic Benefit in Chronic Bronchitis

Por Lambert, James A., Raju, S. Vamsee, Tang, Li Ping, McNicholas, Carmel M., Li, Yao, Courville, Clifford A., Farris, Roopan F., Coricor, George E., Smoot, Lisa H., Mazur, Marina M., Dransfield, Mark T., Bolger, Graeme B., Rowe, Steven M.
Publicado em 2014

Human PDE4A8, a novel brain-expressed PDE4 cAMP-specific phosphodiesterase that has undergone rapid evolutionary change

Por Mackenzie, Kirsty F., Topping, Emma C., Bugaj-Gaweda, Bozena, Deng, Chengjun, Cheung, York-Fong, Olsen, Aileen E., Stockard, Cecil R., High Mitchell, Lisa, Baillie, George S., Grizzle, William E., De Vivo, Michael, Houslay, Miles D., Wang, Daguang, Bolger, Graeme B.
Publicado no Biochem J (2008)