PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization.

par Houslay, Miles D, Adams, David R
Publié 2003

GENOME-SCALE SEQUENCING TO IDENTIFY GENES INVOLVED IN MENDELIAN DISORDERS

par Markello, Thomas C, Adams, David R
Publié 2013

The National Institutes of Health undiagnosed diseases program

par Tifft, Cynthia J., Adams, David R.
Publié dans Curr Opin Pediatr (2014)

RACK1, A multifaceted scaffolding protein: Structure and function

par Adams, David R, Ron, Dorit, Kiely, Patrick A
Publié 2011

Identifying Clinical Terms in Medical Text Using Ontology-Guided Machine Learning

par Arbabi, Aryan, Adams, David R, Fidler, Sanja, Brudno, Michael
Publié dans JMIR Med Inform (2019)

Biofilm-Specific Cross-Species Induction of Antimicrobial Compounds in Bacilli

par Yan, Liming, Boyd, Kenneth G., Adams, David R., Burgess, J. Grant
Publié 2003

Serine Phosphorylation of the Insulin-like Growth Factor I (IGF-1) Receptor C-terminal Tail Restrains Kinase Activity and Cell Growth

par Kelly, Geraldine M., Buckley, Deirdre A., Kiely, Patrick A., Adams, David R., O'Connor, Rosemary
Publié 2012

RACK(1) to the future – a historical perspective

par Ron, Dorit, Adams, David R, Baillie, George S, Long, Aideen, O’Connor, Rosemary, Kiely, Patrick A
Publié 2013

The Potential of a Novel Class of EPAC-Selective Agonists to Combat Cardiovascular Inflammation

par Barker, Graeme, Parnell, Euan, van Basten, Boy, Buist, Hanna, Adams, David R., Yarwood, Stephen J.
Publié dans J Cardiovasc Dev Dis (2017)

Direct Interaction between Scaffolding Proteins RACK1 and 14-3-3ζ Regulates Brain-derived Neurotrophic Factor (BDNF) Transcription

par Neasta, Jérémie, Kiely, Patrick A., He, Dao-Yao, Adams, David R., O'Connor, Rosemary, Ron, Dorit
Publié 2012

Identification of a multifunctional docking site on the catalytic unit of phosphodiesterase-4 (PDE4) that is utilised by multiple interaction partners

par Houslay, Kirsty F., Christian, Frank, MacLeod, Ruth, Adams, David R., Houslay, Miles D., Baillie, George S.
Publié dans Biochem J (2017)

Limited Effects of Endurance or Interval Training on Visceral Adipose Tissue and Systemic Inflammation in Sedentary Middle-Aged Men

par Cooper, Joshua H. F., Collins, Blake E. G., Adams, David R., Robergs, Robert A., Donges, Cheyne E.
Publié dans J Obes (2016)

The Undiagnosed Diseases Program Integrated Collaboration System (UDPICS): One Program’s Experience Developing Custom Software to Support Research for Complex-Disease Families

par Guzman, Jessica, Lee, Elizabeth, Draper, David, Valivullah, Zaheer, Yu, Guoyun, Sincan, Murat, Gahl, William A., Adams, David R.
Publié dans Children (Basel) (2015)

Genomewide significance testing of variation from single case exomes

par Wilfert, Amy B., Chao, Katherine R., Kaushal, Madhurima, Jain, Sanjay, Zöllner, Sebastian, Adams, David R., Conrad, Donald F.
Publié dans Nat Genet (2016)

Retrospective analysis in oculocutaneous albinism patients for the 2.7 kb deletion in the OCA2 gene revealed a co-segregation of the controversial variant, p.R305W

par Gao, Jackson, D’Souza, Leera, Wetherby, Keith, Antolik, Christian, Reeves, Melissa, Adams, David R., Tumminia, Santa, Wang, Xinjing
Publié dans Cell Biosci (2017)

The sphingosine 1-phosphate receptor 2 is shed in exosomes from breast cancer cells and is N-terminally processed to a short constitutively active form that promotes extracellular...

par El Buri, Ashref, Adams, David R., Smith, Douglas, Tate, Rothwelle J., Mullin, Margaret, Pyne, Susan, Pyne, Nigel J.
Publié dans Oncotarget (2018)

Phosphorylation of RACK1 on Tyrosine 52 by c-Abl Is Required for Insulin-like Growth Factor I-mediated Regulation of Focal Adhesion Kinase

par Kiely, Patrick A., Baillie, George S., Barrett, Robert, Buckley, Deirdre A., Adams, David R., Houslay, Miles D., O'Connor, Rosemary
Publié 2009

Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs

par Hudson, Brian D., Christiansen, Elisabeth, Tikhonova, Irina G., Grundmann, Manuel, Kostenis, Evi, Adams, David R., Ulven, Trond, Milligan, Graeme
Publié 2012

Free Sialic Acid Storage Disorder: Progress and Promise

par Huizing, Marjan, Hackbarth, Mary E., Adams, David R, Wasserstein, Melissa, Patterson, Marc C, Walkley, Steven U, Gahl, William A
Publié dans Neurosci Lett (2021)

MEK1 Binds Directly to βArrestin1, Influencing Both Its Phosphorylation by ERK and the Timing of Its Isoprenaline-stimulated Internalization

par Meng, Dong, Lynch, Martin J., Huston, Elaine, Beyermann, Michael, Eichhorst, Jenny, Adams, David R., Klussmann, Enno, Houslay, Miles D., Baillie, George S.
Publié 2009