HIF hydroxylase pathways in cardiovascular physiology and medicine

af Bishop, Tammie, Ratcliffe, Peter J.
Udgivet i Circ Res (2015)

Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives

af Bishop, Tammie, Ratcliffe, Peter J
Udgivet i Hypoxia (Auckl) (2014)

Chapter 21: Hyperplasia of Pulmonary Neuroepithelial Bodies (NEB) in Lungs of Prolyl Hydroxylase –1(PHD-1) Deficient Mice

af Pan, Jie, Yeger, Herman, Ratcliffe, Peter, Bishop, Tammie, Cutz, Ernest
Udgivet i Adv Exp Med Biol (2012)

Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice

af Pan, Jie, Bishop, Tammie, Ratcliffe, Peter J, Yeger, Herman, Cutz, Ernest
Udgivet i Hypoxia (Auckl) (2016)

Hypoxia‐inducible factor 1‐alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl‐4‐hydroxylase 2

af Hulley, Philippa A, Bishop, Tammie, Vernet, Aude, Schneider, Jurgen E, Edwards, James R, Athanasou, Nick A, Knowles, Helen J
Udgivet i J Pathol (2017)

Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice

af Chen, Ruo-Li, Nagel, Simon, Papadakis, Michalis, Bishop, Tammie, Pollard, Patrick, Ratcliffe, Peter J, Pugh, Christopher W, Buchan, Alastair M
Udgivet 2012

Genetic Analysis of Pathways Regulated by the von Hippel-Lindau Tumor Suppressor in Caenorhabditis elegans

af Bishop, Tammie, Lau, Kah Weng, Epstein, Andrew C. R, Kim, Stuart K, Jiang, Min, O'Rourke, Delia, Pugh, Christopher W, Gleadle, Jonathan M, Taylor, Martin S, Hodgkin, Jonathan, Ratcliffe, Peter J
Udgivet 2004

Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway

af Hodson, Emma J., Nicholls, Lynn G., Turner, Philip J., Llyr, Ronan, Fielding, James W., Douglas, Gillian, Ratnayaka, Indrika, Robbins, Peter A., Pugh, Christopher W., Buckler, Keith J., Ratcliffe, Peter J., Bishop, Tammie
Udgivet i J Physiol (2015)

PHD2 inactivation in Type I cells drives HIF‐2α‐dependent multilineage hyperplasia and the formation of paraganglioma‐like carotid bodies

af Fielding, James W., Hodson, Emma J., Cheng, Xiaotong, Ferguson, David J. P., Eckardt, Luise, Adam, Julie, Lip, Philomena, Maton‐Howarth, Matthew, Ratnayaka, Indrika, Pugh, Christopher W., Buckler, Keith J., Ratcliffe, Peter J., Bishop, Tammie
Udgivet i J Physiol (2018)

Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2

af Bishop, Tammie, Talbot, Nick P, Turner, Philip J, Nicholls, Lynn G, Pascual, Alberto, Hodson, Emma J, Douglas, Gillian, Fielding, James W, Smith, Thomas G, Demetriades, Marina, Schofield, Christopher J, Robbins, Peter A, Pugh, Christopher W, Buckler, Keith J, Ratcliffe, Peter J
Udgivet 2013

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

af Chan, Mun Chiang, Atasoylu, Onur, Hodson, Emma, Tumber, Anthony, Leung, Ivanhoe K. H., Chowdhury, Rasheduzzaman, Gómez-Pérez, Verónica, Demetriades, Marina, Rydzik, Anna M., Holt-Martyn, James, Tian, Ya-Min, Bishop, Tammie, Claridge, Timothy D. W., Kawamura, Akane, Pugh, Christopher W., Ratcliffe, Peter J., Schofield, Christopher J.
Udgivet i PLoS One (2015)

Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control

af Cheng, Xiaotong, Prange-Barczynska, Maria, Fielding, James W., Zhang, Minghao, Burrell, Alana L., Lima, Joanna D.C.C., Eckardt, Luise, Argles, Isobel L.A., Pugh, Christopher W., Buckler, Keith J., Robbins, Peter A., Hodson, Emma J., Bruick, Richard K., Collinson, Lucy M., Rastinejad, Fraydoon, Bishop, Tammie, Ratcliffe, Peter J.
Udgivet i J Clin Invest (2020)

Silent hypoxaemia in COVID-19 patients

af Simonson, Tatum S., Baker, Tracy L., Banzett, Robert B., Bishop, Tammie, Dempsey, Jerome A., Feldman, Jack L., Guyenet, Patrice G., Hodson, Emma J., Mitchell, Gordon S., Moya, Esteban A., Nokes, Brandon T., Orr, Jeremy E., Owens, Robert L., Poulin, Marc, Rawling, Jean M., Schmickl, Christopher N., Watters, Jyoti J., Younes, Magdy, Malhotra, Atul
Udgivet i J Physiol (2021)

Systemic silencing of Phd2 causes reversible immune regulatory dysfunction

af Yamamoto, Atsushi, Hester, Joanna, Macklin, Philip S., Kawai, Kento, Uchiyama, Masateru, Biggs, Daniel, Bishop, Tammie, Bull, Katherine, Cheng, Xiaotong, Cawthorne, Eleanor, Coleman, Mathew L., Crockford, Tanya L., Davies, Ben, Dow, Lukas E., Goldin, Rob, Kranc, Kamil, Kudo, Hiromi, Lawson, Hannah, McAuliffe, James, Milward, Kate, Scudamore, Cheryl L., Soilleux, Elizabeth, Issa, Fadi, Ratcliffe, Peter J., Pugh, Chris W.
Udgivet i J Clin Invest (2019)

Abnormal Sympathoadrenal Development and Systemic Hypotension in PHD3(−/−) Mice

af Bishop, Tammie, Gallagher, Denis, Pascual, Alberto, Lygate, Craig A., de Bono, Joseph P., Nicholls, Lynn G., Ortega-Saenz, Patricia, Oster, Henrik, Wijeyekoon, Bhathiya, Sutherland, Andrew I., Grosfeld, Alexandra, Aragones, Julian, Schneider, Martin, van Geyte, Katie, Teixeira, Dania, Diez-Juan, Antonio, Lopez-Barneo, Jose, Channon, Keith M., Maxwell, Patrick H., Pugh, Christopher W., Davies, Alun M., Carmeliet, Peter, Ratcliffe, Peter J.
Udgivet 2008

Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells

af Wing, Peter A.C., Keeley, Thomas P., Zhuang, Xiaodong, Lee, Jeffrey Y., Prange-Barczynska, Maria, Tsukuda, Senko, Morgan, Sophie B., Harding, Adam C., Argles, Isobel L.A., Kurlekar, Samvid, Noerenberg, Marko, Thompson, Craig P., Huang, Kuan-Ying A., Balfe, Peter, Watashi, Koichi, Castello, Alfredo, Hinks, Timothy S.C., James, William, Ratcliffe, Peter J., Davis, Ilan, Hodson, Emma J., Bishop, Tammie, McKeating, Jane A.
Udgivet i Cell Rep (2021)