HIF hydroxylase pathways in cardiovascular physiology and medicine

Autor Bishop, Tammie, Ratcliffe, Peter J.
Vydáno v Circ Res (2015)

Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives

Autor Bishop, Tammie, Ratcliffe, Peter J
Vydáno v Hypoxia (Auckl) (2014)

Chapter 21: Hyperplasia of Pulmonary Neuroepithelial Bodies (NEB) in Lungs of Prolyl Hydroxylase –1(PHD-1) Deficient Mice

Autor Pan, Jie, Yeger, Herman, Ratcliffe, Peter, Bishop, Tammie, Cutz, Ernest
Vydáno v Adv Exp Med Biol (2012)

Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice

Autor Pan, Jie, Bishop, Tammie, Ratcliffe, Peter J, Yeger, Herman, Cutz, Ernest
Vydáno v Hypoxia (Auckl) (2016)

Hypoxia‐inducible factor 1‐alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl‐4‐hydroxylase 2

Autor Hulley, Philippa A, Bishop, Tammie, Vernet, Aude, Schneider, Jurgen E, Edwards, James R, Athanasou, Nick A, Knowles, Helen J
Vydáno v J Pathol (2017)

Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice

Autor Chen, Ruo-Li, Nagel, Simon, Papadakis, Michalis, Bishop, Tammie, Pollard, Patrick, Ratcliffe, Peter J, Pugh, Christopher W, Buchan, Alastair M
Vydáno 2012

Genetic Analysis of Pathways Regulated by the von Hippel-Lindau Tumor Suppressor in Caenorhabditis elegans

Autor Bishop, Tammie, Lau, Kah Weng, Epstein, Andrew C. R, Kim, Stuart K, Jiang, Min, O'Rourke, Delia, Pugh, Christopher W, Gleadle, Jonathan M, Taylor, Martin S, Hodgkin, Jonathan, Ratcliffe, Peter J
Vydáno 2004

Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway

Autor Hodson, Emma J., Nicholls, Lynn G., Turner, Philip J., Llyr, Ronan, Fielding, James W., Douglas, Gillian, Ratnayaka, Indrika, Robbins, Peter A., Pugh, Christopher W., Buckler, Keith J., Ratcliffe, Peter J., Bishop, Tammie
Vydáno v J Physiol (2015)

PHD2 inactivation in Type I cells drives HIF‐2α‐dependent multilineage hyperplasia and the formation of paraganglioma‐like carotid bodies

Autor Fielding, James W., Hodson, Emma J., Cheng, Xiaotong, Ferguson, David J. P., Eckardt, Luise, Adam, Julie, Lip, Philomena, Maton‐Howarth, Matthew, Ratnayaka, Indrika, Pugh, Christopher W., Buckler, Keith J., Ratcliffe, Peter J., Bishop, Tammie
Vydáno v J Physiol (2018)

Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2

Autor Bishop, Tammie, Talbot, Nick P, Turner, Philip J, Nicholls, Lynn G, Pascual, Alberto, Hodson, Emma J, Douglas, Gillian, Fielding, James W, Smith, Thomas G, Demetriades, Marina, Schofield, Christopher J, Robbins, Peter A, Pugh, Christopher W, Buckler, Keith J, Ratcliffe, Peter J
Vydáno 2013

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

Autor Chan, Mun Chiang, Atasoylu, Onur, Hodson, Emma, Tumber, Anthony, Leung, Ivanhoe K. H., Chowdhury, Rasheduzzaman, Gómez-Pérez, Verónica, Demetriades, Marina, Rydzik, Anna M., Holt-Martyn, James, Tian, Ya-Min, Bishop, Tammie, Claridge, Timothy D. W., Kawamura, Akane, Pugh, Christopher W., Ratcliffe, Peter J., Schofield, Christopher J.
Vydáno v PLoS One (2015)

Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control

Autor Cheng, Xiaotong, Prange-Barczynska, Maria, Fielding, James W., Zhang, Minghao, Burrell, Alana L., Lima, Joanna D.C.C., Eckardt, Luise, Argles, Isobel L.A., Pugh, Christopher W., Buckler, Keith J., Robbins, Peter A., Hodson, Emma J., Bruick, Richard K., Collinson, Lucy M., Rastinejad, Fraydoon, Bishop, Tammie, Ratcliffe, Peter J.
Vydáno v J Clin Invest (2020)

Silent hypoxaemia in COVID-19 patients

Autor Simonson, Tatum S., Baker, Tracy L., Banzett, Robert B., Bishop, Tammie, Dempsey, Jerome A., Feldman, Jack L., Guyenet, Patrice G., Hodson, Emma J., Mitchell, Gordon S., Moya, Esteban A., Nokes, Brandon T., Orr, Jeremy E., Owens, Robert L., Poulin, Marc, Rawling, Jean M., Schmickl, Christopher N., Watters, Jyoti J., Younes, Magdy, Malhotra, Atul
Vydáno v J Physiol (2021)

Systemic silencing of Phd2 causes reversible immune regulatory dysfunction

Autor Yamamoto, Atsushi, Hester, Joanna, Macklin, Philip S., Kawai, Kento, Uchiyama, Masateru, Biggs, Daniel, Bishop, Tammie, Bull, Katherine, Cheng, Xiaotong, Cawthorne, Eleanor, Coleman, Mathew L., Crockford, Tanya L., Davies, Ben, Dow, Lukas E., Goldin, Rob, Kranc, Kamil, Kudo, Hiromi, Lawson, Hannah, McAuliffe, James, Milward, Kate, Scudamore, Cheryl L., Soilleux, Elizabeth, Issa, Fadi, Ratcliffe, Peter J., Pugh, Chris W.
Vydáno v J Clin Invest (2019)

Abnormal Sympathoadrenal Development and Systemic Hypotension in PHD3(−/−) Mice

Autor Bishop, Tammie, Gallagher, Denis, Pascual, Alberto, Lygate, Craig A., de Bono, Joseph P., Nicholls, Lynn G., Ortega-Saenz, Patricia, Oster, Henrik, Wijeyekoon, Bhathiya, Sutherland, Andrew I., Grosfeld, Alexandra, Aragones, Julian, Schneider, Martin, van Geyte, Katie, Teixeira, Dania, Diez-Juan, Antonio, Lopez-Barneo, Jose, Channon, Keith M., Maxwell, Patrick H., Pugh, Christopher W., Davies, Alun M., Carmeliet, Peter, Ratcliffe, Peter J.
Vydáno 2008

Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells

Autor Wing, Peter A.C., Keeley, Thomas P., Zhuang, Xiaodong, Lee, Jeffrey Y., Prange-Barczynska, Maria, Tsukuda, Senko, Morgan, Sophie B., Harding, Adam C., Argles, Isobel L.A., Kurlekar, Samvid, Noerenberg, Marko, Thompson, Craig P., Huang, Kuan-Ying A., Balfe, Peter, Watashi, Koichi, Castello, Alfredo, Hinks, Timothy S.C., James, William, Ratcliffe, Peter J., Davis, Ilan, Hodson, Emma J., Bishop, Tammie, McKeating, Jane A.
Vydáno v Cell Rep (2021)