TET proteins and the control of cytosine demethylation in cancer

Por Scourzic, Laurianne, Mouly, Enguerran, Bernard, Olivier A
Publicado no Genome Med (2015)

JAK2(V617F)/TET2 mutations: does the order matter?

Por Pronier, Elodie, Quivoron, Cyril, Bernard, Olivier A., Villeval, Jean-Luc
Publicado em 2011

Spliceosome mutations in myelodysplastic syndromes and chronic myelomonocytic leukemia

Por Chesnais, Virginie, Kosmider, Olivier, Damm, Frederik, Itzykson, Raphael, Bernard, Olivier A., Solary, Eric, Fontenay, Michaela
Publicado em 2012

The t(1;12)(q21;p13) translocation of human acute myeloblastic leukemia results in a TEL-ARNT fusion

Por Salomon-Nguyen, Florence, Della-Valle, Véronique, Mauchauffé, Martine, Busson-Le Coniat, Maryvonne, Ghysdael, Jacques, Berger, Roland, Bernard, Olivier A.
Publicado em 2000

OTT-MAL Is a Deregulated Activator of Serum Response Factor-Dependent Gene Expression

Por Descot, Arnaud, Rex-Haffner, Monika, Courtois, Geneviève, Bluteau, Dominique, Menssen, Antje, Mercher, Thomas, Bernard, Olivier A., Treisman, Richard, Posern, Guido
Publicado em 2008

Ott1 (Rbm15) Is Essential for Placental Vascular Branching Morphogenesis and Embryonic Development of the Heart and Spleen

Por Raffel, Glen D., Chu, Gerald C., Jesneck, Jonathan L., Cullen, Dana E., Bronson, Roderick T., Bernard, Olivier A., Gilliland, D. Gary
Publicado em 2009

Ott1(Rbm15) has pleiotropic roles in hematopoietic development

Por Raffel, Glen D., Mercher, Thomas, Shigematsu, Hirokazu, Williams, Ifor R., Cullen, Dana E., Akashi, Koichi, Bernard, Olivier A., Gilliland, D. Gary
Publicado em 2007

Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis

Por Rasmussen, Kasper D., Jia, Guangshuai, Johansen, Jens V., Pedersen, Marianne T., Rapin, Nicolas, Bagger, Frederik O., Porse, Bo T., Bernard, Olivier A., Christensen, Jesper, Helin, Kristian
Publicado no Genes Dev (2015)

Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia

Por Mercher, Thomas, Coniat, Maryvonne Busson-Le, Monni, Richard, Mauchauffé, Martine, Khac, Florence Nguyen, Gressin, Lætitia, Mugneret, Francine, Leblanc, Thierry, Dastugue, Nicole, Berger, Roland, Bernard, Olivier A.
Publicado em 2001

Functional analysis of the NUP98-CCDC28A fusion protein

Por Petit, Arnaud, Ragu, Christine, Soler, Gwendoline, Ottolenghi, Chris, Schluth, Caroline, Radford-Weiss, Isabelle, Schneider-Maunoury, Sylvie, Callebaut, Isabelle, Dastugue, Nicole, Drabkin, Harry A., Bernard, Olivier A., Romana, Serge, Penard-Lacronique, Virginie
Publicado em 2012

JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model

Por Mercher, Thomas, Wernig, Gerlinde, Moore, Sandra A., Levine, Ross L., Gu, Ting-Lei, Fröhling, Stefan, Cullen, Dana, Polakiewicz, Roberto D., Bernard, Olivier A., Boggon, Titus J., Lee, Benjamin H., Gilliland, D. Gary
Publicado em 2006

TET2 mutations in secondary acute myeloid leukemias: a French retrospective study

Por Kosmider, Olivier, Delabesse, Eric, Mas, Véronique Mansat-De, Cornillet-Lefebvre, Pascale, Blanchet, Odile, Delmer, Alain, Recher, Christian, Raynaud, Sophie, Bouscary, Didier, Viguié, Franck, Lacombe, Catherine, Bernard, Olivier A., Ifrah, Norbert, Dreyfus, François, Fontenay, Michaëla
Publicado em 2011

Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias

Por Kim, Woo Jae, Okimoto, Ross A., Purton, Louise E., Goodwin, Meagan, Haserlat, Sara M., Dayyani, Farshid, Sweetser, David A., McClatchey, Andrea I., Bernard, Olivier A., Look, A. Thomas, Bell, Daphne W., Scadden, David T., Haber, Daniel A.
Publicado em 2008

Heterozygous and Homozygous JAK2(V617F) States Modeled by Induced Pluripotent Stem Cells from Myeloproliferative Neoplasm Patients

Por Saliba, Joseph, Hamidi, Sofiane, Lenglet, Gaëlle, Langlois, Thierry, Yin, Jingkui, Cabagnols, Xénia, Secardin, Lise, Legrand, Céline, Galy, Anne, Opolon, Paule, Benyahia, Baya, Solary, Eric, Bernard, Olivier A., Chen, Longyun, Debili, Najet, Raslova, Hana, Norol, Françoise, Vainchenker, William, Plo, Isabelle, Di Stefano, Antonio
Publicado em 2013

Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response

Por Amatangelo, Michael D., Quek, Lynn, Shih, Alan, Stein, Eytan M., Roshal, Mikhail, David, Muriel D., Marteyn, Benoit, Farnoud, Noushin Rahnamay, de Botton, Stephane, Bernard, Olivier A., Wu, Bin, Yen, Katharine E., Tallman, Martin S., Papaemmanuil, Elli, Penard-Lacronique, Virginie, Thakurta, Anjan, Vyas, Paresh, Levine, Ross L.
Publicado no Blood (2017)

The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model

Por Mercher, Thomas, Raffel, Glen D., Moore, Sandra A., Cornejo, Melanie G., Baudry-Bluteau, Dominique, Cagnard, Nicolas, Jesneck, Jonathan L., Pikman, Yana, Cullen, Dana, Williams, Ifor R., Akashi, Koichi, Shigematsu, Hirokazu, Bourquin, Jean-Pierre, Giovannini, Marco, Vainchenker, William, Levine, Ross L., Lee, Benjamin H., Bernard, Olivier A., Gilliland, D. Gary
Publicado em 2009

Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors

Por Pronier, Elodie, Almire, Carole, Mokrani, Hayat, Vasanthakumar, Aparna, Simon, Audrey, da Costa Reis Monte Mor, Barbara, Massé, Aline, Le Couédic, Jean-Pierre, Pendino, Frédéric, Carbonne, Bruno, Larghero, Jérôme, Ravanat, Jean-Luc, Casadevall, Nicole, Bernard, Olivier A., Droin, Nathalie, Solary, Eric, Godley, Lucy A., Vainchenker, William, Plo, Isabelle, Delhommeau, François
Publicado em 2011

DNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice

Por Scourzic, Laurianne, Couronné, Lucile, Pedersen, Marianne T., Della Valle, Véronique, Diop, M’boyba, Mylonas, Elena, Calvo, Julien, Mouly, Enguerran, Lopez, Cécile K., Martin, Nadine, Fontenay, Michaëla, Bender, Ambre, Guibert, Sylvain, Dubreuil, Patrice, Dessen, Philippe, Droin, Nathalie, Pflumio, Françoise, Weber, Michael, Gaulard, Philippe, Helin, Kristian, Mercher, Thomas, Bernard, Olivier A.
Publicado no Leukemia (2016)

Integrative clinicopathological and molecular analyses of angioimmunoblastic T-cell lymphoma and other nodal lymphomas of follicular helper T-cell origin

Por Dobay, Maria Pamela, Lemonnier, Francois, Missiaglia, Edoardo, Bastard, Christian, Vallois, David, Jais, Jean-Philippe, Scourzic, Laurianne, Dupuy, Aurélie, Fataccioli, Virginie, Pujals, Anais, Parrens, Marie, Le Bras, Fabien, Rousset, Thérèse, Picquenot, Jean-Michel, Martin, Nadine, Haioun, Corinne, Delarue, Richard, Bernard, Olivier A., Delorenzi, Mauro, de Leval, Laurence, Gaulard, Philippe
Publicado no Haematologica (2017)

High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia

Por Loriaux, Marc M., Levine, Ross L., Tyner, Jeffrey W., Fröhling, Stefan, Scholl, Claudia, Stoffregen, Eric P., Wernig, Gerlinde, Erickson, Heidi, Eide, Christopher A., Berger, Roland, Bernard, Olivier A., Griffin, James D., Stone, Richard M., Lee, Benjamin, Meyerson, Matthew, Heinrich, Michael C., Deininger, Michael W., Gilliland, D. Gary, Druker, Brian J.
Publicado em 2008