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TET proteins and the control of cytosine demethylation in cancer

The discovery that ten-eleven translocation (TET) proteins are α-ketoglutarate-dependent dioxygenases involved in the conversion of 5-methylcytosines (5-mC) to 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine and 5-carboxycytosine has revealed new pathways in the cytosine methylation and demethylat...

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Detalhes bibliográficos
Publicado no:Genome Med
Principais autores: Scourzic, Laurianne, Mouly, Enguerran, Bernard, Olivier A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308928/
https://ncbi.nlm.nih.gov/pubmed/25632305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0134-6
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