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TET family dioxygenases and DNA demethylation in stem cells and cancers

The methylation of cytosine and subsequent oxidation constitutes a fundamental epigenetic modification in mammalian genomes, and its abnormalities are intimately coupled to various pathogenic processes including cancer development. Enzymes of the Ten–eleven translocation (TET) family catalyze the st...

詳細記述

保存先:
書誌詳細
出版年:Exp Mol Med
主要な著者: An, Jungeun, Rao, Anjana, Ko, Myunggon
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130217/
https://ncbi.nlm.nih.gov/pubmed/28450733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.5
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